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Synthesis and Structure–Activity of Wee1 inhibitors

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Posted on January 25, 2022 ppbhg

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  • Effectiveness of direct GIRK activators varied somewhat between the two platforms (review Figure ?Number77c with ?with7f),7f), yet pEC50 calculation portrayed 551 while more potent than ML297 and 553 for both methods, and, moreover, classified all remaining analogs while inactive
  • (E) Top graph: Mant-GDP (100 nM) was incubated with increasing concentrations of recombinant Cdc42 for 10 min
  • The thromboembolic events were dissimilar enough to one another that there might have been no unifying explanation
  • We examined regeneration of BDA-traced CST axons 8?weeks after SCI seeing that over
  • At present, after two years of close follow-up, the patient has shown no signs of relapse or conversion to MM

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  • Acetylcholine ??7 Nicotinic Receptors
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  • L-Type Calcium Channels
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  • Non-selective Adenosine
  • Nucleoside Transporters
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  • Oxytocin Receptors
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  • Potassium (KV) Channels
  • Potassium Channels, Non-selective
  • Prostanoid Receptors
  • Protein Kinase B
  • Protein Ser/Thr Phosphatases
  • PTP
  • Retinoid X Receptors
  • Serotonin (5-ht1E) Receptors
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  • Signal Transducers and Activators of Transcription
  • Sirtuin
  • Syk Kinase
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  • Transient Receptor Potential Channels
  • Ubiquitin/Proteasome System
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  • Urotensin-II Receptor
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